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6-Methoxy-N-methylpyridin-2-amine

  • CAS No. 88569-83-9

  • Cat. No. CS-0078649
  • Molecule weight138.17
  • Purity≥97%
  • MDL No.MFCD00191557

*For research and further manufacturing use only, not for direct human use.

6-Methoxy-N-methylpyridin-2-amine|CS-0078649

Structure of 88569-83-9

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General Information

  • CAS No. 88569-83-9
  • Cat. No. CS-0078649
  • Purity ≥97%
  • MDL No. MFCD00191557
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₀N₂O
  • Molecular Weight 138.17
  • Synonym(s) 6-methoxy-N-methyl-, monohydrochloride
  • SMILES CNC1=NC(OC)=CC=C1

Description

6-Methoxy-N-methylpyridin-2-amine features a pyridine core functionalized with a methoxy group at the 6-position and a methylamino substituent at nitrogen, delivering enhanced solubility and electron-donating character. This scaffold serves as a key building block in medicinal chemistry, particularly for kinase inhibitors and bioactive heterocycles.

Application

6-Methoxy-N-methylpyridin-2-amine serves as a versatile building block in medicinal chemistry, enabling rapid access to substituted pyridine scaffolds through standard coupling and functionalization reactions. Its methoxy group provides moderate electron donation and enhances solubility, while the N-methylated pyridine nitrogen offers favorable basicity and metabolic stability. The compound exhibits bench stability, ease of purification, and compatibility with common synthetic transformations, making it well-suited for iterative library synthesis and lead optimization workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   34.15
  • LogP   1.1319
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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