2-Bromo-5-fluoroisonicotinic acid

Name: 2-Bromo-5-fluoroisonicotinic acid
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 885588-12-5
Cat. No. CS-W000432
Purity≥98%
MDL No.MFCD09261246

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-Bromo-5-fluoroisonicotinic acid|CS-W000432

Structure of 885588-12-5

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 885588-12-5
Cat. No. CS-W000432
Purity ≥98%
MDL No. MFCD09261246
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₃BrFNO₂
Molecular Weight 220.00
Synonym(s) 2-Bromo-4-carboxy-5-fluoropyridine; 2-Bromo-5-fluoroisonicotinic acid
SMILES O=C(C1=CC(Br)=NC=C1F)O

Description

2-Bromo-5-fluoroisonicotinic acid features a strategically positioned bromine and fluorine at the pyridine ring's 2- and 5-positions, enabling selective cross-coupling and enhanced electronic tuning. This bench-stable derivative integrates readily into pharmaceutical intermediates, offering high reactivity under mild conditions with minimal side-product formation.

Application

2-Bromo-5-fluoroisonicotinic acid serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its orthogonal halogenation pattern. The bromo and fluoro substituents facilitate sequential functionalization, while the carboxylic acid group supports direct derivatization or activation for amide bond formation. Its bench-stable crystalline form simplifies handling and purification, making it well-suited for iterative synthesis of heterocyclic scaffolds and API intermediates.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 50.19
LogP 1.6814
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Carboxylic Acid

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

2-Bromo-5-fluoroisonicotinic acid sigma2-Bromo-5-fluoroisonicotinic acid manufacturer2-Bromo-5-fluoroisonicotinic acid price2-Bromo-5-fluoroisonicotinic acid structure2-Bromo-5-fluoroisonicotinic acid SDSbuy 2-Bromo-5-fluoroisonicotinic acid2-Bromo-5-fluoroisonicotinic acid supplier2-Bromo-5-fluoroisonicotinic acid uses2-Bromo-5-fluoroisonicotinic acid molecular weightprice of 2-Bromo-5-fluoroisonicotinic acid2-Bromo-5-fluoroisonicotinic acid chemical name formula of 2-Bromo-5-fluoroisonicotinic acid

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2-Bromo-5-fluoroisonicotinic acid

CAS No. 885588-12-5

Recommended Products