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CS-W001157 4
Total: USD 88.00

Dibenzyl (chloromethyl) phosphate

  • CAS No. 258516-84-6

  • Cat. No. CS-W007628
  • Purity≥95%
  • MDL No.MFCD16652586

*For research and further manufacturing use only, not for direct human use.

Dibenzyl (chloromethyl) phosphate|CS-W007628

Structure of 258516-84-6

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General Information

  • CAS No. 258516-84-6
  • Cat. No. CS-W007628
  • Purity ≥95%
  • MDL No. MFCD16652586
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₁₆ClO₄P
  • Molecular Weight 326.71
  • Synonym(s) Dibenzyl chloromethyl phosphate
  • SMILES O=P(OCC1=CC=CC=C1)(OCC2=CC=CC=C2)OCCl

Description

.

Application

Dibenzyl (chloromethyl) phosphate serves as a versatile phosphorylating agent in synthetic organic chemistry, enabling efficient introduction of phosphonate functionality under mild conditions. Its bench-stable nature and compatibility with diverse functional groups facilitate straightforward incorporation into complex molecular architectures. The chloromethyl moiety enables subsequent derivatization via nucleophilic substitution, making it valuable for constructing phosphorus-containing building blocks in medicinal chemistry and catalytic systems.

Synthesis

  • Route1
    • null|null
      49715-04-0
    • ~43%
    • In-stock
      Dibenzyl (chloromethyl) phosphate|CS-W007628
      258516-84-6

    References

    • WO2008/14602 A1, ; Page/Page column 56-58 ;
  • Route2
    • null|null
      49715-04-0
    • In-stock
      Dibenzyl phosphate|CS-W008704
      1623-08-1
    • ~91%
    • In-stock
      Dibenzyl (chloromethyl) phosphate|CS-W007628
      258516-84-6

    References

    • Tetrahedron Letters, , vol. 43, # 21 p. 3793 - 3794
  • Route3
    • null|null
      3518-65-8
    • In-stock
      Dibenzyl phosphate|CS-W008704
      1623-08-1
    • ~66%
    • In-stock
      Dibenzyl (chloromethyl) phosphate|CS-W007628
      258516-84-6

    References

    • Journal of the American Chemical Society, , vol. 133, # 31 p. 12021 - 12030

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07,GHS08
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H372
Precautionary Statements : P260-P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   44.76
  • LogP   4.741
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   8

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