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Structure of 885520-26-3
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4,6-Difluoro-1H-indazole is a fluorinated heterocyclic scaffold featuring two strategically positioned fluorine atoms that enhance electron deficiency and metabolic stability. This configuration enables efficient coupling in cross-coupling reactions and improves membrane permeability. The molecule integrates readily into bioactive compounds for medicinal chemistry applications.
4,6-Difluoro-1H-indazole serves as a versatile building block in medicinal chemistry, enabling direct functionalization at electron-deficient positions via palladium-catalyzed cross-coupling. Its enhanced reactivity profile facilitates efficient C–H arylation and heterocycle elaboration, while maintaining bench stability and compatibility with common protecting groups. This compound functions as a key scaffold for targeted synthesis of bioactive molecules, particularly in kinase inhibitor development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: