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CS-W001157 4
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4-Bromo-6-chloro-1H-indazole

  • CAS No. 885519-03-9

  • Cat. No. CS-D1585
  • Purity≥96%
  • MDL No.MFCD07781352

*For research and further manufacturing use only, not for direct human use.

4-Bromo-6-chloro-1H-indazole|CS-D1585

Structure of 885519-03-9

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General Information

  • CAS No. 885519-03-9
  • Cat. No. CS-D1585
  • Purity ≥96%
  • MDL No. MFCD07781352
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₄BrClN₂
  • Molecular Weight 231.48
  • Synonym(s) None
  • SMILES BrC1=CC(Cl)=CC2=C1C=NN2

Description

4-Bromo-6-chloro-1H-indazole features a fused bicyclic core with complementary halogen substituents enabling selective cross-coupling and functionalization. The electron-deficient indazole scaffold supports diverse derivatization in medicinal chemistry, while the orthogonal reactivity of bromo and chloro groups permits sequential transformations under mild conditions.

Application

4-Bromo-6-chloro-1H-indazole serves as a versatile heterocyclic building block for medicinal chemistry and materials science. Its dual halogen substituents enable palladium-catalyzed cross-coupling reactions, facilitating the construction of biaryl and functionalized indazole scaffolds. The compound exhibits excellent bench stability, ease of handling, and compatibility with standard synthetic workflows, making it ideal for rapid diversification in lead optimization campaigns.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   28.68
  • LogP   2.9788
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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