4-Aminopicolinamide

Name: 4-Aminopicolinamide
Brand: ChemScene
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CAS No. 100137-47-1
Cat. No. CS-0139155
Purity≥96%
MDL No.MFCD08062892

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 100137-47-1

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General Information

CAS No. 100137-47-1
Cat. No. CS-0139155
Purity ≥96%
MDL No. MFCD08062892
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₇N₃O
Molecular Weight None
Synonym(s) 2-Pyridinecarboxamide,4-amino-(9CI)
SMILES O=C(N)C1=NC=CC(N)=C1

Description

4-Aminopicolinamide features a pyridine ring bearing both an amide and primary amine at the 4-position, enabling dual functionalization. This scaffold integrates readily into bioactive molecules, leveraging its polarity and hydrogen-bonding capacity for enhanced solubility and target engagement in medicinal chemistry applications.

Application

4-Aminopicolinamide serves as a versatile building block in medicinal chemistry, enabling the synthesis of pyridine-based pharmacophores. Its dual functionality—pyridine nitrogen and amide group—supports diverse transformations, including coupling reactions and derivatization. The compound exhibits good bench stability and facilitates purification via standard crystallization or chromatography methods, making it well-suited for scalable synthesis workflows.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

TPSA 82
LogP -0.2373
H_Acceptors 3
H_Donors 2
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Amide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

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4-Aminopicolinamide

CAS No. 100137-47-1

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