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CS-W001157 4
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2-Methyloxazole-5-carbaldehyde

  • CAS No. 885273-42-7

  • Cat. No. CS-W021727
  • Purity≥95%
  • MDL No.MFCD06738689

*For research and further manufacturing use only, not for direct human use.

2-Methyloxazole-5-carbaldehyde|CS-W021727

Structure of 885273-42-7

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General Information

  • CAS No. 885273-42-7
  • Cat. No. CS-W021727
  • Purity ≥95%
  • MDL No. MFCD06738689
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₅NO₂
  • Molecular Weight 111.10
  • Synonym(s) 2-Methyl-1,3-oxazole-5-carbaldehyde
  • SMILES CC1=NC=C(O1)C=O

Description

2-Methyloxazole-5-carbaldehyde features a fused oxazole ring with a methyl group at the 2-position and a formyl moiety at the 5-position, delivering high reactivity in heterocyclic synthesis. This electron-deficient carbonyl system facilitates efficient coupling reactions and serves as a key building block for bioactive molecules and functional materials.

Application

2-Methyloxazole-5-carbaldehyde serves as a versatile heterocyclic building block for medicinal chemistry and synthetic organic applications. Its aldehyde functionality enables efficient imine formation, reductive amination, and coupling reactions, while the oxazole ring provides metabolic stability and structural rigidity. The methyl group enhances electronic modulation and facilitates downstream functionalization. This compound exhibits excellent bench stability and is compatible with common reaction conditions, making it a practical choice for constructing complex scaffolds in API development and library synthesis.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   43.1
  • LogP   0.79552
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

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