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CS-W001157 4
Total: USD 88.00

tert-Butyl 2,6-diazaspiro[3.4]octane-2-carboxylate

  • CAS No. 885270-84-8

  • Cat. No. CS-W020658
  • Purity≥95%
  • MDL No.MFCD08234737

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 2,6-diazaspiro[3.4]octane-2-carboxylate|CS-W020658

Structure of 885270-84-8

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General Information

  • CAS No. 885270-84-8
  • Cat. No. CS-W020658
  • Purity ≥95%
  • MDL No. MFCD08234737
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₂₀N₂O₂
  • Molecular Weight 212.29
  • Synonym(s) 2,6-Diaza-spiro[3.4]octane-2-carboxylic acid tert-butyl
  • SMILES O=C(OC(C)(C)C)N1CC2(CNCC2)C1

Description

tert-Butyl 2,6-diazaspiro[3.4]octane-2-carboxylate features a rigid spirocyclic core with two nitrogen atoms at the 2- and 6-positions, delivering enhanced conformational control. The tert-butyl ester group ensures excellent stability and ease of handling under standard conditions. This scaffold serves as a key building block in the synthesis of constrained heterocycles for medicinal chemistry applications.

Application

tert-Butyl 2,6-diazaspiro[3.4]octane-2-carboxylate serves as a versatile spirocyclic scaffold for medicinal chemistry and catalytic synthesis. Its rigid, bicyclic structure supports stereochemical control in asymmetric transformations and functions as a protected diamine building block. The tert-butyl ester enables straightforward deprotection under mild acidic conditions, facilitating downstream functionalization. This compound exhibits excellent bench stability and compatibility with diverse reaction conditions, making it suitable for modular synthesis of complex heterocycles and bioactive molecules.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   41.57
  • LogP   1.2168
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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