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CS-W001157 4
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2-Methyl-2,6-diazaspiro[3.4]octane

  • CAS No. 135380-30-2

  • Cat. No. CS-0000661
  • Purity≥97%
  • MDL No.MFCD13180704

*For research and further manufacturing use only, not for direct human use.

2-Methyl-2,6-diazaspiro[3.4]octane|CS-0000661

Structure of 135380-30-2

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General Information

  • CAS No. 135380-30-2
  • Cat. No. CS-0000661
  • Purity ≥97%
  • MDL No. MFCD13180704
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₄N₂
  • Molecular Weight 126.20
  • Synonym(s) In1122 Impurity 69
  • SMILES CN1CC2(CNCC2)C1

Description

2-Methyl-2,6-diazaspiro[3.4]octane features a rigid spirocyclic core with strategically positioned nitrogen atoms, enabling strong coordination in transition metal complexes. The methyl substitution enhances steric shielding and improves stability under standard bench conditions. This scaffold serves as a robust ligand platform for catalytic applications requiring defined geometry and electronic tuning.

Application

2-Methyl-2,6-diazaspiro[3.4]octane serves as a rigid, bicyclic scaffold enabling precise spatial orientation of functional groups in medicinal chemistry applications. Its spirocyclic structure provides enhanced metabolic stability and conformational control, while the tertiary amine centers facilitate salt formation and solubility optimization. The molecule exhibits excellent bench stability and compatibility with standard coupling reactions, making it a valuable building block for constructing complex heterocyclic architectures and targeted API intermediates.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   15.27
  • LogP   -0.0885
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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