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Methyl imidazo[1,2-a]pyridine-5-carboxylate

  • CAS No. 88047-55-6

  • Cat. No. CS-0053764
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Methyl imidazo[1,2-a]pyridine-5-carboxylate|CS-0053764

Structure of 88047-55-6

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General Information

  • CAS No. 88047-55-6
  • Cat. No. CS-0053764
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₈N₂O₂
  • Molecular Weight 176.17
  • Synonym(s) methyl imidazopyridine-5-carboxylate
  • SMILES O=C(C1=CC=CC2=NC=CN12)OC

Description

Methyl imidazo[1,2-a]pyridine-5-carboxylate is a heterocyclic ester featuring a fused imidazo[1,2-a]pyridine core with a methyl carboxylate handle. This scaffold integrates electron-rich aromaticity with a reactive ester group, enabling direct incorporation into synthetic sequences. The compound exhibits bench-stable handling and compatibility with diverse reaction conditions, facilitating efficient access to complex nitrogen-containing architectures in medicinal chemistry and materials synthesis.

Application

Methyl imidazo[1,2-a]pyridine-5-carboxylate serves as a versatile heterocyclic building block for medicinal chemistry and catalytic synthesis. Its fused imidazo[1,2-a]pyridine core provides robust structural rigidity and enhanced metabolic stability, while the ester functionality enables straightforward derivatization via hydrolysis, reduction, or coupling reactions. The molecule exhibits good bench stability and facilitates efficient access to bioactive scaffolds in drug discovery programs.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   43.6
  • LogP   1.1209
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   1

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