Imidazo[1,2-a]pyridin-5-ylmethanol

Name: Imidazo[1,2-a]pyridin-5-ylmethanol
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CAS No. 167884-17-5
Cat. No. CS-0084723
Purity≥97%
MDL No.MFCD13183181

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Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
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Imidazo[1,2-a]pyridin-5-ylmethanol|CS-0084723

Structure of 167884-17-5

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General Information

CAS No. 167884-17-5
Cat. No. CS-0084723
Purity ≥97%
MDL No. MFCD13183181
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₈N₂O
Molecular Weight 148.16
Synonym(s) Imidazo[1,2-a]pyridine-5-methanol (9CI)
SMILES OCC1=CC=CC2=NC=CN12

Description

Imidazo[1,2-a]pyridin-5-ylmethanol delivers a rigid heteroaromatic scaffold with a reactive hydroxymethyl group, enabling direct functionalization in medicinal chemistry. This bench-stable, moisture-tolerant building block integrates efficiently into kinase inhibitors and bioactive scaffolds, offering enhanced solubility and metabolic stability in drug discovery applications.

Application

Imidazo[1,2-a]pyridin-5-ylmethanol serves as a versatile building block for heterocyclic synthesis, enabling efficient access to bioactive scaffolds through standard functional group transformations. Its bench-stable nature and compatibility with diverse reaction conditions facilitate straightforward derivatization, including oxidation to the aldehyde or esterification, supporting applications in medicinal chemistry and process development.

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H320-H335
Precautionary Statements : P261-P280-P302+P352

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Computational Chemistry Data

TPSA 37.53
LogP 0.8266
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 1

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Imidazole compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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Imidazo[1,2-a]pyridin-5-ylmethanol

CAS No. 167884-17-5

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