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CS-W001157 4
Total: USD 88.00

Azido-PEG6-CH2COOH

  • CAS No. 880129-82-8

  • Cat. No. CS-0148084
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Azido-PEG6-CH2COOH|CS-0148084

Structure of 880129-82-8

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General Information

  • CAS No. 880129-82-8
  • Cat. No. CS-0148084
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₂₇N₃O₈
  • Molecular Weight 365.38
  • Synonym(s) None
  • SMILES O=C(O)COCCOCCOCCOCCOCCOCCN=[N+]=[N-]

Description

Azido-PEG6-CH2COOH features a C6 polyethylene glycol spacer linking an azide group to a carboxylic acid moiety. This bifunctional reagent enables site-specific conjugation via copper-free click chemistry and offers enhanced solubility in aqueous systems. The terminal carboxyl group facilitates coupling to amine-containing biomolecules under standard conditions.

Application

Azido-PEG6-CH2COOH serves as a versatile bifunctional linker for bioconjugation and polymer chemistry. The azide group enables efficient strain-promoted or copper-catalyzed cycloaddition reactions, while the carboxylic acid facilitates amide bond formation with amines. The six-ethylene glycol units provide excellent solubility and spacer length, enhancing accessibility in aqueous environments. This compound offers robust bench stability, ease of purification, and functional group tolerance, making it ideal for constructing site-specific conjugates and functionalized polymers in drug delivery and diagnostic applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   141.44
  • LogP   0.4809
  • H_Acceptors   8
  • H_Donors   1
  • Rotatable_Bonds   20

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