Methyl 4-bromo-2-chloro-6-methylbenzoate

Name: Methyl 4-bromo-2-chloro-6-methylbenzoate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 877149-10-5
Cat. No. CS-W022846
Molecule weightNone
Purity≥98%
MDL No.MFCD09260942

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Methyl 4-bromo-2-chloro-6-methylbenzoate|CS-W022846

Structure of 877149-10-5

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 877149-10-5
Cat. No. CS-W022846
Purity ≥98%
MDL No. MFCD09260942
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₉H₈BrClO₂
Molecular Weight None
Synonym(s) oMo-2-chloro-6-Methyl-Benzoic acid Methyl ester
SMILES COC(=O)C1=C(Cl)C=C(Br)C=C1C

Description

Methyl 4-bromo-2-chloro-6-methylbenzoate features a trifunctional aromatic core with strategically positioned halogens and a methyl group, enabling selective cross-coupling reactions. The electron-deficient ring facilitates palladium-catalyzed transformations, while the ester handle supports downstream derivatization. This bench-stable compound integrates readily into complex molecular architectures under standard conditions.

Application

Methyl 4-bromo-2-chloro-6-methylbenzoate serves as a versatile ortho-functionalized building block in medicinal chemistry and agrochemical synthesis. Its bromo and chloro substituents enable palladium-catalyzed cross-coupling reactions, while the methyl group provides steric and electronic modulation. The ester functionality offers compatibility with standard reduction and derivatization protocols, facilitating access to diverse core structures. Bench-stable and readily purified by column chromatography, it supports scalable, reproducible synthetic workflows.

Synthesis

Route1
- 186581-53-3
- In-stock
  
  877149-07-0
- ~99%
- In-stock
  
  877149-10-5
References
- ASTRAZENECA AB; NPS PHARMACEUTICALS, INC. Patent: WO2006/20879 A1, 2006 ; Location in patent: Page/Page column 60 ; WO 2006/020879 A1

Safety Information

Download SDS

GHS Pictogram : N/A	GHS No : N/A
Signal Word : N/A	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 26.3
LogP 3.19752
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Functional Group Ester

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

Methyl 4-bromo-2-chloro-6-methylbenzoate sigmaMethyl 4-bromo-2-chloro-6-methylbenzoate manufacturerMethyl 4-bromo-2-chloro-6-methylbenzoate priceMethyl 4-bromo-2-chloro-6-methylbenzoate structureMethyl 4-bromo-2-chloro-6-methylbenzoate SDSbuy Methyl 4-bromo-2-chloro-6-methylbenzoateMethyl 4-bromo-2-chloro-6-methylbenzoate supplierMethyl 4-bromo-2-chloro-6-methylbenzoate usesMethyl 4-bromo-2-chloro-6-methylbenzoate molecular weightprice of Methyl 4-bromo-2-chloro-6-methylbenzoateMethyl 4-bromo-2-chloro-6-methylbenzoate chemical name formula of Methyl 4-bromo-2-chloro-6-methylbenzoate

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

Methyl 4-bromo-2-chloro-6-methylbenzoate

CAS No. 877149-10-5

Recommended Products