4-Bromo-2-chloro-6-methylbenzoic acid

Name: 4-Bromo-2-chloro-6-methylbenzoic acid
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 877149-07-0
Cat. No. CS-0132647
Molecule weight249.49
Purity≥98%
MDL No.MFCD19686179

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4-Bromo-2-chloro-6-methylbenzoic acid|CS-0132647

Structure of 877149-07-0

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 877149-07-0
Cat. No. CS-0132647
Purity ≥98%
MDL No. MFCD19686179
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₆BrClO₂
Molecular Weight 249.49
Synonym(s) Benzoic acid, 4-broMo-2-chloro-6-Methyl-
SMILES O=C(O)C1=C(C)C=C(Br)C=C1Cl

Description

4-Bromo-2-chloro-6-methylbenzoic acid features a sterically hindered aromatic core with complementary halogen and methyl substituents, enabling selective cross-coupling reactions. The carboxylic acid group provides a robust handle for peptide coupling, esterification, or metal complexation under standard conditions. This bench-stable derivative delivers high functional group tolerance in synthetic sequences requiring precise regiocontrol.

Application

4-Bromo-2-chloro-6-methylbenzoic acid serves as a versatile building block in medicinal chemistry and agrochemical synthesis, offering orthogonal halogenation sites for palladium-catalyzed cross-coupling reactions. The carboxylic acid group enables direct derivatization into amides, esters, or acyl chlorides, while the methyl group provides a site for oxidation or functionalization. Its bench-stable crystalline form facilitates handling and purification, and the strategic placement of bromo, chloro, and methyl substituents supports diverse late-stage modifications in target-oriented synthesis.

Synthesis

Route1
- In-stock
  
  68837-59-2
- ~74%
- In-stock
  
  877149-07-0
References
- Trabanco, Andres A.; Duvey, Guillaume; Cid, Jose Maria; MacDonald, Gregor J.; Cluzeau, Philippe; Nhem, Vanthea; Furnari, Rocco; Behaj, Nadia; Poulain, Geraldine; Finn, Terry; Lavreysen, Hilde; Poli, Sonia; Raux, Alexandre; Thollon, Yves; Poirier, Nicolas; DAddona, David; Andres, Jose Ignacio; Lutjens, Robert; Poul, Emmanuel Le; Imogai, Hassan; Rocher, Jean-Philippe Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 3 p. 971 - 976

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 37.3
LogP 3.10912
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Carboxylic Acid

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

4-Bromo-2-chloro-6-methylbenzoic acid sigma4-Bromo-2-chloro-6-methylbenzoic acid manufacturer4-Bromo-2-chloro-6-methylbenzoic acid price4-Bromo-2-chloro-6-methylbenzoic acid structure4-Bromo-2-chloro-6-methylbenzoic acid SDSbuy 4-Bromo-2-chloro-6-methylbenzoic acid4-Bromo-2-chloro-6-methylbenzoic acid supplier4-Bromo-2-chloro-6-methylbenzoic acid uses4-Bromo-2-chloro-6-methylbenzoic acid molecular weightprice of 4-Bromo-2-chloro-6-methylbenzoic acid4-Bromo-2-chloro-6-methylbenzoic acid chemical name formula of 4-Bromo-2-chloro-6-methylbenzoic acid

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

4-Bromo-2-chloro-6-methylbenzoic acid

CAS No. 877149-07-0

Recommended Products