2-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline

Name: 2-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 876922-75-7
Cat. No. CS-0108810
Molecule weight269.15
Purity≥98%
MDL No.MFCD22418301

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline|CS-0108810

Structure of 876922-75-7

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 876922-75-7
Cat. No. CS-0108810
Purity ≥98%
MDL No. MFCD22418301
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₆H₂₀BNO₂
Molecular Weight 269.15
Synonym(s) 2-Methyl-quinoline-5-boronic acid pinacol ester
SMILES CC1(C)C(C)(C)OB(C2=C3C=CC(C)=NC3=CC=C2)O1

Description

2-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline is a bench-stable boronate reagent featuring a sterically protected boryl group attached to a quinoline scaffold. This configuration enables efficient Suzuki-Miyaura cross-coupling under mild conditions, delivering functionalized quinoline derivatives with high regioselectivity and minimal protodeboronation.

Application

2-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline serves as a robust boronate building block for palladium-catalyzed cross-coupling reactions. Its quinoline scaffold offers enhanced stability and favorable electronic properties, enabling efficient Suzuki-Miyaura coupling with aryl, vinyl, and heteroaryl halides. The tetramethylboronate group ensures excellent shelf life, low toxicity, and ease of purification, making it ideal for modular synthesis of biologically relevant heterocycles and advanced pharmaceutical intermediates.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H320-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 31.35
LogP 2.84242
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 1

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds quinoline compounds

Key Words

876922-75-7 sigma876922-75-7 manufacturer876922-75-7 price876922-75-7 structure876922-75-7 SDSbuy 876922-75-7876922-75-7 supplier876922-75-7 uses876922-75-7 molecular weightprice of 876922-75-7876922-75-7 chemical name formula of 876922-75-7

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline

CAS No. 876922-75-7

Recommended Products