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CS-W001157 4
Total: USD 88.00

2-Methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol

  • CAS No. 269410-22-2

  • Cat. No. CS-0036776
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-Methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol|CS-0036776

Structure of 269410-22-2

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General Information

  • CAS No. 269410-22-2
  • Cat. No. CS-0036776
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₉BO₄
  • Molecular Weight 250.10
  • Synonym(s) None
  • SMILES CC1(C)C(C)(C)OB(C2=CC=C(C(=C2)OC)O)O1

Application

2-Methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol serves as a robust boronate building block for Suzuki-Miyaura coupling reactions. Its ortho-methoxy group provides enhanced stability and facilitates selective functionalization in complex molecule synthesis. The tetramethyl-substituted dioxaborolane moiety ensures excellent bench stability, low toxicity, and compatibility with diverse reaction conditions, enabling efficient C–C bond formation under mild, aqueous-compatible protocols.

Synthesis

  • Route1
    • In-stock
      4-Bromo-2-methoxyphenol|CS-W007865
      7368-78-7
    • null|null
      25015-63-8
    • ~62%
    • In-stock
      2-Methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol|CS-0036776
      269410-22-2

    References

    • US6680401 B1, ; Page column 66 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   47.92
  • LogP   1.7
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   2

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