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CS-W001157 4
Total: USD 88.00

2-(1-Methylpiperidin-4-yl)acetic acid

  • CAS No. 87647-06-1

  • Cat. No. CS-0054612
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-(1-Methylpiperidin-4-yl)acetic acid|CS-0054612

Structure of 87647-06-1

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General Information

  • CAS No. 87647-06-1
  • Cat. No. CS-0054612
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₅NO₂
  • Molecular Weight 157.21
  • Synonym(s) 2-(1-methyl-4-piperidyl)acetic acid
  • SMILES CN1CCC(CC(O)=O)CC1

Description

This piperidine-based carboxylic acid features a flexible alkyl chain linking a basic amine to a polar terminal acid group. The 1-methylpiperidin-4-yl moiety enhances solubility and metabolic stability, while the acetic acid functionality enables conjugation or salt formation. Ideal for medicinal chemistry applications requiring modulated lipophilicity and targeted bioavailability.

Application

2-(1-Methylpiperidin-4-yl)acetic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive molecules through its amine-functionalized side chain. The piperidine core provides favorable solubility and metabolic stability, while the carboxylic acid group facilitates straightforward derivatization via amide bond formation or esterification. This scaffold is particularly valuable for constructing targeted therapeutics, offering robust bench stability and compatibility with standard purification techniques.

Synthesis

  • Route1
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      50-00-0
    • In-stock
      4-Piperidineacetic acid|CS-W002877
      51052-78-9
    • ~%
    • In-stock
      2-(1-Methylpiperidin-4-yl)acetic acid|CS-0054612
      87647-06-1

    References

    • US5880128 A1, ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   40.54
  • LogP   0.8029
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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