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Structure of 876-33-5
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O-(4-Methoxybenzyl)hydroxylamine hydrochloride offers a stable, moisture-tolerant platform for selective N-arylation reactions. The electron-rich methoxy group enhances nucleophilicity, while the benzylic linker enables straightforward deprotection under mild acidic conditions. This reagent integrates efficiently into synthetic sequences requiring protected hydroxylamine functionality.
O-(4-Methoxybenzyl)hydroxylamine hydrochloride serves as a stable, bench-ready precursor for the synthesis of oxime derivatives and nitrogen-containing heterocycles. Its protected hydroxylamine functionality enables selective C–N bond formation under mild conditions, with excellent functional group tolerance and straightforward purification via crystallization or acid-base extraction. Widely employed in medicinal chemistry campaigns for amine bioisostere replacement and scaffold diversification, it facilitates efficient access to pharmacologically relevant scaffolds through reliable reductive amination and cyclization protocols.
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GHS Pictogram :
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GHS No : GHS02,GHS07
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Signal Word : Danger
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UN#: 1325
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Class : 4.1
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Packing Group : Ⅲ
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Hazard Statements : H228-H315-H319
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Precautionary Statements : P210-P240-P264-P280-P370+P378
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Lot numbers can be found on the outside label of a product: