Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

O-(4-Methoxybenzyl)hydroxylamine

  • CAS No. 21038-22-2

  • Cat. No. CS-W004482
  • Molecule weight153.18
  • Purity≥95%
  • MDL No.MFCD01722038

*For research and further manufacturing use only, not for direct human use.

O-(4-Methoxybenzyl)hydroxylamine|CS-W004482

Structure of 21038-22-2

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 21038-22-2
  • Cat. No. CS-W004482
  • Purity ≥95%
  • MDL No. MFCD01722038
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₁NO₂
  • Molecular Weight 153.18
  • Synonym(s) O-[(4-methoxyphenyl)methyl]Hydroxylamine
  • SMILES NOCc1ccc(cc1)OC

Description

O-(4-Methoxybenzyl)hydroxylamine delivers a protected hydroxylamine handle ideal for selective conjugation in bioconjugate chemistry. The methoxybenzyl group provides enhanced stability and solubility, enabling efficient incorporation into peptide and oligonucleotide workflows under standard conditions.

Application

O-(4-Methoxybenzyl)hydroxylamine serves as a stable, bench-friendly protecting group for hydroxylamine, enabling selective N-alkylation and oxime formation under mild conditions. Its orthogonality to common functional groups facilitates use in complex molecule synthesis, while the p-methoxybenzyl moiety allows for efficient deprotection via acid-labile cleavage. Functions reliably in both small-molecule and peptide-based scaffold construction.

Synthesis

  • Route1
    • null|null
      2014-61-1
    • ~97%
    • In-stock
      O-(4-Methoxybenzyl)hydroxylamine|CS-W004482
      21038-22-2

    References

    • Iha, Rhiannon K.; Van Horn, Brooke A.; Wooley, Karen L. Journal of Polymer Science, Part A: Polymer Chemistry, 2010 , vol. 48, # 16 p. 3553 - 3563
  • Route2
    • In-stock
      N-tert-Butoxycarbonylhydroxylamine|CS-W001934
      36016-38-3
    • null|null
      824-94-2
    • ~38%
    • In-stock
      O-(4-Methoxybenzyl)hydroxylamine|CS-W004482
      21038-22-2

    References

    • Halazy, Serge; Quattropani, Anna; Scheer, Alexander; Schwarz, Mattias; Thomas, Russell; Baxter, Antony Patent: US2003/212012 A1, 2003 ;
  • Route3

    References

    • Schumann,E.L. et al. Journal of Medicinal Chemistry, 1964 , vol. 7, p. 329 - 334

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS06
Signal Word : Danger
UN#: 2735
Class : 8
Packing Group : Ⅱ
Hazard Statements : H301-H314-H335-H412
Precautionary Statements : P261-P264-P270-P271-P273-P280-P301+P330+P331-P304+P340-P363-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   44.48
  • LogP   1.0855
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • O-(4-Methoxybenzyl)hydroxylamine sigmaO-(4-Methoxybenzyl)hydroxylamine manufacturerO-(4-Methoxybenzyl)hydroxylamine priceO-(4-Methoxybenzyl)hydroxylamine structureO-(4-Methoxybenzyl)hydroxylamine SDSbuy O-(4-Methoxybenzyl)hydroxylamineO-(4-Methoxybenzyl)hydroxylamine supplierO-(4-Methoxybenzyl)hydroxylamine usesO-(4-Methoxybenzyl)hydroxylamine molecular weightprice of O-(4-Methoxybenzyl)hydroxylamineO-(4-Methoxybenzyl)hydroxylamine chemical name formula of O-(4-Methoxybenzyl)hydroxylamine
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label