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CS-W001157 4
Total: USD 88.00

O-(4-Fluorobenzyl)hydroxylamine hydrochloride

  • CAS No. 51572-89-5

  • Cat. No. CS-0043692
  • Molecule weight177.60
  • Purity≥98%
  • MDL No.MFCD01114581

*For research and further manufacturing use only, not for direct human use.

O-(4-Fluorobenzyl)hydroxylamine hydrochloride|CS-0043692

Structure of 51572-89-5

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General Information

  • CAS No. 51572-89-5
  • Cat. No. CS-0043692
  • Purity ≥98%
  • MDL No. MFCD01114581
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₉ClFNO
  • Molecular Weight 177.60
  • Synonym(s) O-[(4-Fluorophenyl)methyl]hydroxylamine hydrochloride
  • SMILES NOCC1=CC=C(C=C1)F.[H]Cl

Description

O-(4-Fluorobenzyl)hydroxylamine hydrochloride delivers a reactive hydroxylamine handle tethered to a fluorinated benzyl moiety, enabling efficient conjugation in bioorthogonal labeling and synthetic peptide modification. The electron-withdrawing fluorine enhances nucleophilicity while maintaining stability under standard conditions.

Application

O-(4-Fluorobenzyl)hydroxylamine hydrochloride serves as a stable, bench-ready building block for the synthesis of fluorinated oximes and heterocycles. Its reactivity enables efficient coupling with carbonyl compounds under mild conditions, facilitating access to biologically relevant scaffolds. The hydrochloride salt enhances solubility and handling, while the 4-fluorobenzyl group provides orthogonal functionality for downstream modifications in medicinal chemistry workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS02,GHS07
Signal Word : Danger
UN#: 1325
Class : 4.1
Packing Group : Ⅲ
Hazard Statements : H228-H315-H319
Precautionary Statements : P210-P240-P264-P280-P370+P378

Quality Control

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Computational Chemistry Data

  • TPSA   35.25
  • LogP   1.6378
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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