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CS-W001157 4
Total: USD 88.00

O-Benzylhydroxylamine hydrochloride

  • CAS No. 2687-43-6

  • Cat. No. CS-W008676
  • Purity≥97%
  • MDL No.MFCD00012952

*For research and further manufacturing use only, not for direct human use.

O-Benzylhydroxylamine hydrochloride|CS-W008676

Structure of 2687-43-6

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General Information

  • CAS No. 2687-43-6
  • Cat. No. CS-W008676
  • Purity ≥97%
  • MDL No. MFCD00012952
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₀ClNO
  • Molecular Weight None
  • Synonym(s) None
  • SMILES NOCC1=CC=CC=C1.[H]Cl

Description

C13-113-tetra tail is an ionizable lipid molecule containing a polar amino alcohol head group, four hydrophobic carbon-13 tails, and a tertiary amine linker. The lipoid can be formulated into a lipid nanoparticle (LNP) to deliver anionic substrates in vitro and in vivo. This includes siRNA to induce gene silencing in a sequence-specific manner, CAS9 mRNA, and cytotoxic proteins.

Synthesis

  • Route1
    • 2-(Benzyloxy)isoindoline-1,3-dione|CS-0779638
      16653-19-3
    • ~92%
    • In-stock
      O-Benzylhydroxylamine hydrochloride|CS-W008676
      2687-43-6

    References

    • Uhlmann, Peter; Felding, Jakob; Vedso, Per; Begtrup, Mikael Journal of Organic Chemistry, 1997 , vol. 62, # 26 p. 9177 - 9181
  • Route2
    • null|null
      681856-02-0
    • ~60%
    • In-stock
      O-Benzylhydroxylamine hydrochloride|CS-W008676
      2687-43-6

    References

    • Hassner, Alfred; Patchornik, Guy; Pradhan, Tarun K.; Kumareswaran Journal of Organic Chemistry, 2007 , vol. 72, # 2 p. 658 - 661
  • Route3
    • null|null
      3532-25-0
    • ~68%
    • In-stock
      O-Benzylhydroxylamine hydrochloride|CS-W008676
      2687-43-6

    References

    • Singha, A. S.; Misra, B. N. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1982 , vol. 21, # 4 p. 361 - 363

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H315-H317-H318
Precautionary Statements : P261-P264-P272-P280-P302+P352-P362+P364-P501

Quality Control

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Computational Chemistry Data

  • TPSA   35.25
  • LogP   1.4987
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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