H-D-Tyr-OtBu

Name: H-D-Tyr-OtBu
Brand: ChemScene
Availability: InStock
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CAS No. 87553-74-0
Cat. No. CS-0154862
Purity≥97%
MDL No.MFCD00191035

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Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 87553-74-0

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Description

H-D-Tyr-OtBu is a protected tyrosine derivative featuring a tert-butyl ester group, enabling stable incorporation into peptide chains. This bench-stable building block facilitates efficient solid-phase synthesis, with the phenolic hydroxyl group available for selective modification.

Application

H-D-Tyr-OtBu serves as a robust building block for peptide synthesis, offering enhanced stability and ease of handling compared to unprotected tyrosine derivatives. The OtBu protecting group ensures orthogonality during multistep syntheses, while the D-configuration provides resistance to enzymatic degradation. It facilitates efficient coupling reactions and simplifies purification, making it ideal for constructing bioactive peptides and cyclic scaffolds in medicinal chemistry workflows.

General Information

CAS No. 87553-74-0
Cat. No. CS-0154862
Purity ≥97%
MDL No. MFCD00191035
Storage 4°C, protect from light, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₃H₁₉NO₃
Molecular Weight 237.29
Synonym(s) tert-butyl D-tyrosinate
SMILES CC(C)(C)OC(=O)[C@@H](CC1=CC=C(C=C1)O)N

Computational Chemistry Data

TPSA 72.55
LogP 1.6037
H_Acceptors 4
H_Donors 2
Rotatable_Bonds 3

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Phenol

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Life Science Amino Acids and their Derivatives Tyrosine and derivatives

Chemical Biology Peptide Chemistry Unnatural Amino Acid Derivatives

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H-D-Tyr-OtBu

CAS No. 87553-74-0

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