Lot numbers can be found on the outside label of a product:
Z-Tyr-OtBu
-
CAS No. 16881-33-7
- Cat. No. CS-0040973
- Purity≥98%
- MDL No.MFCD00191166
*For research and further manufacturing use only, not for direct human use.
Structure of 16881-33-7
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 16881-33-7
- Cat. No. CS-0040973
- Purity ≥98%
- MDL No. MFCD00191166
- Storage 4°C
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₂₁H₂₅NO₅
- Molecular Weight 371.43
- Synonym(s) None
- SMILES OC(C=C1)=CC=C1C[C@@H](C(OC(C)(C)C)=O)NC(OCC2=CC=CC=C2)=O
Description
Z-Tyr-OtBu is a protected tyrosine derivative featuring a benzyl carbamate (Z) group at the N-terminus and a tert-butyl ester at the C-terminus. This combination enables stable incorporation into peptide chains under standard coupling conditions, with orthogonal deprotection options for selective removal of either protecting group during synthetic workflows.
Application
Z-Tyr-OtBu serves as a key protected tyrosine building block in peptide synthesis, offering stable benzyl protection of the amine and tert-butyl ester functionality for orthogonal handling. It facilitates efficient coupling reactions with minimal racemization, enables straightforward deprotection under standard conditions, and is well-suited for iterative solid-phase and solution-phase strategies. Its bench-stable nature supports reliable handling and purification in complex sequence assembly.
Synthesis
-
Route1
-
In-stock
16874-12-7 -
501-53-1 - ~95%
-
In-stock
16881-33-7
References
-
Palmer, Francine N.; Lach, Franck; Poriel, Cyril; Pepper, Adrian G.; Bagley, Mark C.; Slawin, Alexandra M. Z.; Moody, Christopher J. Organic and Biomolecular Chemistry, 2005 , vol. 3, # 20 p. 3805 - 3811
-
-
Route2
-
In-stock
1164-16-5 -
115-11-7
- ~%
-
In-stock
16881-33-7
References
-
Anderson,G.W.; Callahan,F.M. Journal of the American Chemical Society, 1960 , vol. 82, p. 3359 - 3363
-
-
Route3
-
507-19-7
-
In-stock
1164-16-5
- ~88%
-
In-stock
16881-33-7
References
-
Chevallet, Pierre; Garrouste, Patrick; Malawska, Barbara; Martinez, Jean Tetrahedron Letters, 1993 , vol. 34, # 46 p. 7409 - 7412
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 84.86
- LogP 3.5714
- H_Acceptors 5
- H_Donors 2
- Rotatable_Bonds 6
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- Z-Tyr-OtBu sigmaZ-Tyr-OtBu manufacturerZ-Tyr-OtBu priceZ-Tyr-OtBu structureZ-Tyr-OtBu SDSbuy Z-Tyr-OtBuZ-Tyr-OtBu supplierZ-Tyr-OtBu usesZ-Tyr-OtBu molecular weightprice of Z-Tyr-OtBuZ-Tyr-OtBu chemical name formula of Z-Tyr-OtBu