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CS-W001157 4
Total: USD 88.00

2,3-Dihydro-1H-indene-2-carboxylic acid

  • CAS No. 25177-85-9

  • Cat. No. CS-W010861
  • Purity≥98%
  • MDL No.MFCD00085095

*For research and further manufacturing use only, not for direct human use.

2,3-Dihydro-1H-indene-2-carboxylic acid|CS-W010861

Structure of 25177-85-9

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General Information

  • CAS No. 25177-85-9
  • Cat. No. CS-W010861
  • Purity ≥98%
  • MDL No. MFCD00085095
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₀O₂
  • Molecular Weight 162.19
  • Synonym(s) Indancarboxylicacid
  • SMILES OC(=O)C1CC2=CC=CC=C2C1

Description

A useful synthetic intermediate. 6-Bromonicotinaldehyde is used in wittig reaction. Hydrodehalogenation of 6-bromonicotinaldehyde to produce alcohol.

Application

2,3-Dihydro-1H-indene-2-carboxylic acid serves as a versatile scaffold in medicinal chemistry and synthetic organic research. Its benzylic carboxylic acid functionality enables direct derivatization via amide coupling, esterification, or decarboxylation protocols. The rigid, partially saturated indene core provides structural constraint beneficial for target-specific ligand design, while the bench-stable, crystalline form facilitates handling and purification. Functions effectively in standard peptide coupling and heterocycle construction workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   1.486
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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