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CS-W001157 4
Total: USD 88.00

2-(1H-Indol-1-yl)acetic acid

  • CAS No. 24297-59-4

  • Cat. No. CS-W005380
  • Purity≥95%
  • MDL No.MFCD00047262

*For research and further manufacturing use only, not for direct human use.

2-(1H-Indol-1-yl)acetic acid|CS-W005380

Structure of 24297-59-4

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General Information

  • CAS No. 24297-59-4
  • Cat. No. CS-W005380
  • Purity ≥95%
  • MDL No. MFCD00047262
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₉NO₂
  • Molecular Weight None
  • Synonym(s) Indole-1-acetic Acid
  • SMILES O=C(O)CN1C=CC2=C1C=CC=C2

Description

2-(1H-Indol-1-yl)acetic acid features a bioactive indole core linked to a carboxylic acid side chain, enabling direct integration into peptide conjugates and small-molecule libraries. This scaffold supports rapid derivatization for probing receptor-ligand interactions in neurochemical and oncology research.

Application

2-(1H-Indol-1-yl)acetic acid serves as a versatile building block for indole-based bioactive molecules, enabling straightforward incorporation into pharmaceutical and agrochemical scaffolds. Its carboxylic acid functionality facilitates direct amidation, esterification, or coupling reactions under standard conditions. The molecule exhibits bench stability and tolerates diverse functional groups, making it well-suited for medicinal chemistry campaigns requiring efficient access to indole-containing compounds.

Synthesis

  • Route1
    • null|null
      910322-01-9
    • ~85%
    • In-stock
      2-(1H-Indol-1-yl)acetic acid|CS-W005380
      24297-59-4

    References

    • VICURON PHARMACEUTICALS INC. Patent: US2006/211603 A1, 2006 ; Location in patent: Page/Page column 52 ;
  • Route2
    • Indole, ≥99%|CS-1268948
      120-72-9
    • null|null
      105-36-2
    • ~94%
    • In-stock
      2-(1H-Indol-1-yl)acetic acid|CS-W005380
      24297-59-4

    References

    • Yeda Research and Development Co. Ltd. Patent: US4139703 A1, 1979 ;
  • Route3
    • null|null
      61155-69-9
    • ~%
    • In-stock
      2-(1H-Indol-1-yl)acetic acid|CS-W005380
      24297-59-4

    References

    • Journal of Heterocyclic Chemistry, , vol. 21, p. 975 - 976

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H318
Precautionary Statements : P264-P270-P280-P305+P351+P338-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   42.23
  • LogP   1.7259
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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