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CS-W001157 4
Total: USD 88.00

2-Methyloxetan-3-one

  • CAS No. 87385-83-9

  • Cat. No. CS-0051833
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-Methyloxetan-3-one|CS-0051833

Structure of 87385-83-9

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General Information

  • CAS No. 87385-83-9
  • Cat. No. CS-0051833
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₆O₂
  • Molecular Weight 86.09
  • Synonym(s) None
  • SMILES CC1OCC1=O

Description

2-Methyloxetan-3-one is a strained, four-membered cyclic ketone featuring a reactive oxetane ring with a methyl substituent at the 2-position. This structural motif imparts high ring strain and enhanced electrophilicity, enabling efficient ring-opening reactions under mild conditions. The molecule serves as a valuable building block in synthetic organic chemistry, particularly for constructing complex heterocycles and bioactive scaffolds through nucleophilic addition processes. Its bench-stable nature facilitates handling and integration into multi-step syntheses.

Application

2-Methyloxetan-3-one serves as a versatile synthetic building block for strained three-membered cyclic ketones, enabling efficient access to oxetane-containing scaffolds via nucleophilic addition or ring-opening reactions. Its bench-stable nature and compatibility with diverse functional groups facilitate integration into medicinal chemistry workflows, particularly in the construction of bioactive heterocycles and drug-like molecular frameworks.

Safety Information

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GHS Pictogram :
GHS No : GHS02,GHS07
Signal Word : Danger
UN#: 1993
Class : 3
Packing Group : Ⅲ
Hazard Statements : H225-H315-H319
Precautionary Statements : P210-P233-P240-P241-P242-P243-P264-P280-P302+P352-P362+P364-P370+P378-P501

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Computational Chemistry Data

  • TPSA   26.3
  • LogP   -0.0258
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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