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CS-W001157 4
Total: USD 88.00

1-Chloro-4-ethynylbenzene

  • CAS No. 873-73-4

  • Cat. No. CS-W018322
  • Purity≥98%
  • MDL No.MFCD00191917

*For research and further manufacturing use only, not for direct human use.

1-Chloro-4-ethynylbenzene|CS-W018322

Structure of 873-73-4

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General Information

  • CAS No. 873-73-4
  • Cat. No. CS-W018322
  • Purity ≥98%
  • MDL No. MFCD00191917
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₅Cl
  • Molecular Weight 136.58
  • Synonym(s) 4-Chlorophenylacetylene; 1-Chloro-4-ethynylbenzene
  • SMILES C#CC1=CC=C(Cl)C=C1

Description

1-Chloro-4-ethynylbenzene features a terminal alkyne group conjugated to an electron-deficient aryl chloride, enabling efficient copper-catalyzed coupling reactions. This robust scaffold integrates readily into complex molecular architectures under standard conditions, offering high functional group tolerance and stability during process development workflows.

Synthesis

  • Route1

    References

    • Wang, Yue; Huang, Bin; Sheng, Shouri; Cai, Mingzhong Journal of Chemical Research, 2007 , # 12 p. 728 - 732
  • Route2
    • In-stock
      1-Chloro-4-iodobenzene|CS-W007395
      637-87-6
    • null|null
      471-25-0
    • ~20%
    • In-stock
      1-Chloro-4-ethynylbenzene|CS-W018322
      873-73-4

    References

    • Park, Kyungho; Palani, Thiruvengadam; Pyo, Ayoung; Lee, Sunwoo Tetrahedron Letters, 2012 , vol. 53, # 7 p. 733 - 737
  • Route3
    • In-stock
      1-Chloro-4-iodobenzene|CS-W007395
      637-87-6
    • null|null
      1066-54-2
    • ~%
    • In-stock
      1-Chloro-4-ethynylbenzene|CS-W018322
      873-73-4

    References

    • Catalysis Communications, , vol. 47, p. 40 - 44

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02,GHS07
Signal Word : Danger
UN#: 1325
Class : 4.1
Packing Group : Ⅲ
Hazard Statements : H228-H315-H319-H335
Precautionary Statements : P210-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   0
  • LogP   2.3213
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   0

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