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CS-W001157 4
Total: USD 88.00

(5-(Methoxycarbonyl)pyridin-3-yl)boronic acid

  • CAS No. 871329-53-2

  • Cat. No. CS-W023044
  • Purity≥97%
  • MDL No.MFCD07363742

*For research and further manufacturing use only, not for direct human use.

(5-(Methoxycarbonyl)pyridin-3-yl)boronic acid|CS-W023044

Structure of 871329-53-2

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General Information

  • CAS No. 871329-53-2
  • Cat. No. CS-W023044
  • Purity ≥97%
  • MDL No. MFCD07363742
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈BNO₄
  • Molecular Weight 180.95
  • Synonym(s) Methyl 5-borononicotinate, Methyl 5-boronopyridine-3-carboxylate
  • SMILES OB(C1=CN=CC(C(OC)=O)=C1)O

Description

This boronic acid features a pyridine ring functionalized with a methoxycarbonyl group at the 5-position and a boronic acid moiety at the 3-position, enabling efficient Suzuki-Miyaura coupling. The electron-deficient pyridine ring enhances reactivity, while the ester group provides stability and facilitates downstream transformations.

Application

(5-(Methoxycarbonyl)pyridin-3-yl)boronic acid serves as a versatile building block in Suzuki-Miyaura coupling reactions, enabling efficient C–C bond formation with aryl and vinyl halides. The pyridine core provides enhanced solubility and stability, while the methoxycarbonyl group offers orthogonal reactivity for subsequent derivatization. Its bench-stable nature and compatibility with diverse functional groups facilitate streamlined synthesis of complex heterocyclic scaffolds and pharmaceutical intermediates.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   79.65
  • LogP   -1.452
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   2

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