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CS-W001157 4
Total: USD 88.00

(6-(Methoxycarbonyl)pyridin-3-yl)boronic acid

  • CAS No. 1072945-86-8

  • Cat. No. CS-0082390
  • Purity≥96%
  • MDL No.MFCD09800559

*For research and further manufacturing use only, not for direct human use.

(6-(Methoxycarbonyl)pyridin-3-yl)boronic acid|CS-0082390

Structure of 1072945-86-8

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General Information

  • CAS No. 1072945-86-8
  • Cat. No. CS-0082390
  • Purity ≥96%
  • MDL No. MFCD09800559
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈BNO₄
  • Molecular Weight 180.95
  • Synonym(s) (2-Methylcarboxy)pyridine-5-boronic acid
  • SMILES OB(C1=CN=C(C(OC)=O)C=C1)O

Description

This boronate moiety integrates a pyridine-based scaffold with a methoxycarbonyl group, enabling efficient cross-coupling under mild conditions. The electron-deficient pyridine ring enhances reactivity in Suzuki-Miyaura transformations, while the ester functionality provides tunable solubility and stability. This compound serves as a robust building block for functionalized heterocycles in medicinal chemistry and materials science.

Application

(6-(Methoxycarbonyl)pyridin-3-yl)boronic acid serves as a versatile building block in Suzuki-Miyaura coupling reactions, enabling efficient construction of biaryl and heteroaryl architectures. The pyridine core provides orthogonal reactivity, while the methoxycarbonyl group offers stability and compatibility with standard synthetic workflows. Bench-stable and readily purified, it facilitates scalable synthesis of functionalized heterocycles relevant to medicinal chemistry and materials science.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H315-H318-H335
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

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Computational Chemistry Data

  • TPSA   79.65
  • LogP   -1.452
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   2

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