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4-chloro-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrrolo[2,3-b]pyridine

  • CAS No. 869335-19-3

  • Cat. No. CS-0004717
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-chloro-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrrolo[2,3-b]pyridine|CS-0004717

Structure of 869335-19-3

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General Information

  • CAS No. 869335-19-3
  • Cat. No. CS-0004717
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₉ClN₂OSi
  • Molecular Weight 282.84
  • Synonym(s) 1H-Pyrrolo[2,3-b]pyridine, 4-chloro-1-[[2-(trimethylsilyl)ethoxy]methyl]-
  • SMILES ClC1=C(C=C2)C(N2COCC[Si](C)(C)C)=NC=C1

Synthesis

  • Route1

    References

    • INCYTE CORPORATION Patent: WO2006/69080 A2, 2006 ; Location in patent: Page/Page column 37-38 ; WO 2006/069080 A2
  • Route2
    • null|null
      1221714-47-1
    • ~%
    • 4-chloro-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrrolo[2,3-b]pyridine|CS-0004717
      869335-19-3

    References

    • Heinrich, Timo; Seenisamy, Jeyaprakashnarayanan; Emmanuvel, Lourdusamy; Kulkarni, Santosh S.; Bomke, Joerg; Rohdich, Felix; Greiner, Hartmut; Esdar, Christina; Krier, Mireille; Graedler, Ulrich; Musil, Djordje Journal of Medicinal Chemistry, 2013 , vol. 56, # 3 p. 1160 - 1170

Safety Information

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GHS Pictogram : N/A
GHS No : N/A
Signal Word : N/A
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

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Computational Chemistry Data

  • TPSA   27.05
  • LogP   4.002
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   5

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