Lot numbers can be found on the outside label of a product:
Fmoc-Gly-Val-OH
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CAS No. 86895-14-9
- Cat. No. CS-W014467
- Purity≥98%
- MDL No.MFCD00190884
*For research and further manufacturing use only, not for direct human use.
Structure of 86895-14-9
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General Information
- CAS No. 86895-14-9
- Cat. No. CS-W014467
- Purity ≥98%
- MDL No. MFCD00190884
- Storage 4°C
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₂₂H₂₄N₂O₅
- Molecular Weight 396.44
- Synonym(s) N-Fmoc-glycyl-L-valine
- SMILES O=C([C@H](C(C)C)NC(CNC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)=O)O
Description
Fmoc-Gly-Val-OH is a protected dipeptide building block designed for solid-phase peptide synthesis. The Fmoc group enables orthogonal protection of the α-amino function, while the valine side chain remains unmodified. This derivative offers high stability under standard bench conditions and integrates seamlessly into iterative coupling protocols, streamlining the assembly of complex peptide sequences.
Application
Fmoc-Gly-Val-OH serves as a key building block in solid-phase peptide synthesis, enabling efficient sequential coupling of amino acids. The Fmoc group provides orthogonal protection for the α-amino function, allowing selective deprotection under mild basic conditions. Its glycine-valine sequence offers high solubility and reduced aggregation during synthesis, while the valine side chain supports diverse downstream modifications. This dipeptide is bench-stable, easily purified by recrystallization or chromatography, and widely used in the construction of therapeutic peptides and bioactive scaffolds.
Synthesis
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Route1
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159922-56-2 - ~10%
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In-stock
86895-14-9
References
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Nakahara, Yoshiaki; Iijima, Hiroyuki; Ogawa, Tomoya Tetrahedron Letters, 1994 , vol. 35, # 20 p. 3321 - 3324
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Route2
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In-stock
29022-11-5 - ~%
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In-stock
86895-14-9
References
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Tetrahedron Letters, , vol. 35, # 20 p. 3321 - 3324
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Route3
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In-stock
13211-31-9 - ~%
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In-stock
86895-14-9
References
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Tetrahedron Letters, , vol. 35, # 20 p. 3321 - 3324
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Safety Information
Download SDS|
GHS Pictogram :
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GHS No : GHS05,GHS07,GHS09
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Signal Word : Danger
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UN#: 3077
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Class : 9
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Packing Group : Ⅲ
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Hazard Statements : H302+H312-H315-H318-H411
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Precautionary Statements : P264-P270-P273-P280-P302+P352-P330-P362+P364-P391-P501
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Quality Control
Computational Chemistry Data
- TPSA 104.73
- LogP 2.7505
- H_Acceptors 4
- H_Donors 3
- Rotatable_Bonds 7
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Key Words
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