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CS-W001157 4
Total: USD 88.00

Fmoc-Val-Gly-OH

  • CAS No. 142810-19-3

  • Cat. No. CS-0202097
  • Purity≥98%
  • MDL No.MFCD18427309

*For research and further manufacturing use only, not for direct human use.

Fmoc-Val-Gly-OH|CS-0202097

Structure of 142810-19-3

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General Information

  • CAS No. 142810-19-3
  • Cat. No. CS-0202097
  • Purity ≥98%
  • MDL No. MFCD18427309
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₂H₂₄N₂O₅
  • Molecular Weight 396.44
  • Synonym(s) None
  • SMILES CC([C@H](NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)C(NCC(O)=O)=O)C

Description

Fmoc-Val-Gly-OH serves as a key dipeptide building block in solid-phase peptide synthesis. The fluorenylmethoxy carbonyl (Fmoc) group enables orthogonal protection, while the valine-glycine sequence provides a stable, easily cleavable linkage. This compound facilitates efficient coupling and high-yield chain elongation under standard conditions.

Application

Fmoc-Val-Gly-OH serves as a key building block in solid-phase peptide synthesis, offering robust protection of the N-terminus via the fluorenylmethoxy carbonyl (Fmoc) group. The valine-glycine dipeptide sequence provides excellent solubility and compatibility with standard coupling conditions, while the C-terminal carboxylic acid enables efficient activation and amide bond formation. Its bench-stable nature and straightforward purification make it a practical choice for synthesizing bioactive peptides and peptidomimetics.

Safety Information

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GHS Pictogram :
GHS No : GHS05,GHS09
Signal Word : Danger
UN#: 3077
Class : 9
Packing Group : Ⅲ
Hazard Statements : H302+H312-H315-H318-H411
Precautionary Statements : P264-P270-P302+P352-P330-P391-P501

Quality Control

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Computational Chemistry Data

  • TPSA   104.73
  • LogP   2.7505
  • H_Acceptors   4
  • H_Donors   3
  • Rotatable_Bonds   7

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