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CS-W001157 4
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2-[4-({[(9h-fluoren-9-yl)methoxy]carbonyl}amino)piperidin-1-yl]acetic acid

  • CAS No. 221352-82-5

  • Cat. No. CS-0216031
  • Purity≥97%
  • MDL No.MFCD01321021

*For research and further manufacturing use only, not for direct human use.

2-[4-({[(9h-fluoren-9-yl)methoxy]carbonyl}amino)piperidin-1-yl]acetic acid|CS-0216031

Structure of 221352-82-5

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General Information

  • CAS No. 221352-82-5
  • Cat. No. CS-0216031
  • Purity ≥97%
  • MDL No. MFCD01321021
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₂H₂₄N₂O₄
  • Molecular Weight 380.44
  • Synonym(s) None
  • SMILES O=C(OCC1C=2C=CC=CC2C=3C=CC=CC31)NC4CCN(CC(=O)O)CC4

Description

This fluorenylmethoxycarbonyl-protected piperidine derivative features a C-terminal carboxylic acid for coupling reactions. The robust Fmoc group enables efficient solid-phase peptide synthesis, while the piperidine scaffold provides a versatile handle for modular peptide and peptidomimetic construction under standard conditions.

Application

2-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)piperidin-1-yl]acetic acid serves as a versatile protected amino acid building block for peptide synthesis, enabling efficient incorporation of piperidine-derived side chains. The Fmoc group provides orthogonal protection with high stability under basic conditions and facilitates mild deprotection. Its acetic acid functionality supports conjugation via amide bond formation, while the piperidinyl moiety offers enhanced solubility and structural diversity in synthetic peptide libraries.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   78.87
  • LogP   3.0741
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   5

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