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CS-W001157 4
Total: USD 88.00

6-(4-Fluorophenyl)picolinic acid

  • CAS No. 863704-60-3

  • Cat. No. CS-0187172
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

6-(4-Fluorophenyl)picolinic acid|CS-0187172

Structure of 863704-60-3

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General Information

  • CAS No. 863704-60-3
  • Cat. No. CS-0187172
  • Purity ≥96%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₈FNO₂
  • Molecular Weight 217.20
  • Synonym(s) 6-(4-Fluorophenyl)-picolinic acid
  • SMILES C1=CC(=NC(=C1)C(=O)O)C2=CC=C(C=C2)F

Synthesis

  • Route1
    • In-stock
      6-Bromopicolinic acid|CS-W009049
      21190-87-4
    • null|null
      225916-39-2
    • ~39%
    • 6-(4-Fluorophenyl)picolinic acid|CS-0187172
      863704-60-3

    References

    • Bristol-Myers Squibb Company Patent: US2007/60613 A1, 2007 ; Location in patent: Page/Page column 18-19 ; US 20070060613 A1
  • Route2
    • null|null
      225916-39-2
    • ~40%
    • 6-(4-Fluorophenyl)picolinic acid|CS-0187172
      863704-60-3

    References

    • Borzilleri, Robert M.; Cornelius, Lyndon A.M.; Schmidt, Robert J.; Schroeder, Gretchen M.; Kim, Kyoung S. Patent: US2005/245530 A1, 2005 ; Location in patent: Page/Page column 65 ; US 20050245530 A1
  • Route3
    • Methyl 6-(4-fluorophenyl)picolinate|CS-0749069
      1390624-20-0
    • ~59%
    • 6-(4-Fluorophenyl)picolinic acid|CS-0187172
      863704-60-3

    References

    • CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS (CNIO); PASTOR FERNANDEZ, Joaquin; ALVAREZ ESCOBAR, Rosa Maria; GARCIA GARCIA, Ana Belen; RIESCO FAGUNDO, Rosario Concepcion; BLANCO APARICIO, Carmen Patent: WO2012/98387 A1, 2012 ; Location in patent: Page/Page column 84 ; WO 2012/098387 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H332-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   50.19
  • LogP   2.5859
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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