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CS-W001157 4
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4-Benzyloxy-2-hydroxypyridine

  • CAS No. 53937-02-3

  • Cat. No. CS-B0802
  • Purity≥98%
  • MDL No.MFCD00191783

*For research and further manufacturing use only, not for direct human use.

4-Benzyloxy-2-hydroxypyridine|CS-B0802

Structure of 53937-02-3

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General Information

  • CAS No. 53937-02-3
  • Cat. No. CS-B0802
  • Purity ≥98%
  • MDL No. MFCD00191783
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₁NO₂
  • Molecular Weight 201.22
  • Synonym(s) 4-Benzyloxypyridin-2-one
  • SMILES OC1=NC=CC(OCC2=CC=CC=C2)=C1

Description

4-Benzyloxy-2-hydroxypyridine features a strategically positioned hydroxyl group flanked by electron-withdrawing pyridine and benzyloxy substituents, enabling selective functionalization in synthetic routes. This bench-stable scaffold integrates readily into bioactive heterocycles, offering enhanced solubility and metabolic stability for medicinal chemistry applications.

Synthesis

  • Route1
    • null|null
      2683-66-1
    • ~49%
    • In-stock
      4-Benzyloxy-2-hydroxypyridine|CS-B0802
      53937-02-3

    References

    • EP1741703 A1, ; Page/Page column 62-63 ; EP 1741703 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   42.35
  • LogP   2.3662
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

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