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CS-W001157 4
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4-(Chloromethyl)tetrahydro-2H-pyran

  • CAS No. 863324-23-6

  • Cat. No. CS-0069602
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-(Chloromethyl)tetrahydro-2H-pyran|CS-0069602

Structure of 863324-23-6

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General Information

  • CAS No. 863324-23-6
  • Cat. No. CS-0069602
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₁ClO
  • Molecular Weight 134.60
  • Synonym(s) 4-(Chloromethyl)tetrahydropyran
  • SMILES ClCC1CCOCC1

Description

4-(Chloromethyl)tetrahydro-2H-pyran delivers a reactive chloromethyl handle tethered to a stable tetrahydropyran ring, enabling efficient functionalization in synthetic transformations. This bench-stable, moisture-tolerant reagent integrates readily into complex molecular architectures under standard conditions.

Application

4-(Chloromethyl)tetrahydro-2H-pyran serves as a versatile bifunctional building block, enabling efficient installation of both ether and reactive alkyl chloride functionalities. Its bench-stable nature and compatibility with nucleophilic substitution reactions facilitate straightforward derivatization in synthesis of glycosyl analogs, protected polyols, and heterocyclic scaffolds. Functions as a key intermediate in the construction of complex carbohydrate motifs and bioactive molecules requiring orthogonal functional group handling.

Safety Information

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GHS Pictogram :
GHS No : GHS02,GHS05
Signal Word : Danger
UN#: 2924
Class : 3,8
Packing Group : Ⅲ
Hazard Statements : H225-H314
Precautionary Statements : P210-P233-P240-P241-P242-P243-P260-P264-P280-P301+P330+P331-P304+P340-P363-P370+P378-P405-P501

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Computational Chemistry Data

  • TPSA   9.23
  • LogP   1.6518
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

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