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CS-W001157 4
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2,5-Diaminobenzoic acid

  • CAS No. 610-74-2

  • Cat. No. CS-0113090
  • Purity≥97%
  • MDL No.MFCD00127689

*For research and further manufacturing use only, not for direct human use.

2,5-Diaminobenzoic acid|CS-0113090

Structure of 610-74-2

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General Information

  • CAS No. 610-74-2
  • Cat. No. CS-0113090
  • Purity ≥97%
  • MDL No. MFCD00127689
  • Storage RT, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈N₂O₂
  • Molecular Weight 152.15
  • Synonym(s) 5-Aminoanthranilic acid
  • SMILES O=C(O)C1=CC(N)=CC=C1N

Description

2,5-Diaminobenzoic acid features two amino groups positioned ortho to a carboxylic acid moiety on a benzene ring, enabling versatile conjugation in bioconjugate chemistry and peptide synthesis. The electron-rich aromatic core supports efficient coupling reactions under mild conditions, while the dual amine functionality facilitates site-specific derivatization. This compound serves as a key scaffold for developing functionalized intermediates in medicinal chemistry and materials science applications.

Application

2,5-Diaminobenzoic acid serves as a versatile building block in medicinal chemistry and materials science, enabling the synthesis of bioactive heterocycles and functional polymers. Its dual amine functionality facilitates conjugation reactions, while the carboxylic acid group supports coupling protocols under standard conditions. The compound exhibits good bench stability and is readily purified by recrystallization, making it well-suited for iterative synthetic workflows in API development and probe design.

Synthesis

  • Route1
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      610-28-6
    • ~%
    • In-stock
      2,5-Diaminobenzoic acid|CS-0113090
      610-74-2

    References

    • Chemische Berichte, , vol. 7, p. 1224
  • Route2

    References

    • Chemische Berichte, , vol. 5, p. 201 Journal fuer Praktische Chemie (Leipzig), , vol. <2> 5, p. 241
  • Route3
    • 3,6-Dinitrophthalic acid|CS-0775607
      2300-16-5
    • ~%
    • In-stock
      2,5-Diaminobenzoic acid|CS-0113090
      610-74-2

    References

    • Chemische Berichte, , vol. 15, p. 2721

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

Quality Control

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Computational Chemistry Data

  • TPSA   89.34
  • LogP   0.5492
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   1

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