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CS-W001157 4
Total: USD 88.00

Fmoc-Lys(Z)-OH

  • CAS No. 86060-82-4

  • Cat. No. CS-W011498
  • Purity≥96%
  • MDL No.MFCD00065662

*For research and further manufacturing use only, not for direct human use.

Fmoc-Lys(Z)-OH|CS-W011498

Structure of 86060-82-4

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General Information

  • CAS No. 86060-82-4
  • Cat. No. CS-W011498
  • Purity ≥96%
  • MDL No. MFCD00065662
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₉H₃₀N₂O₆
  • Molecular Weight 502.56
  • Synonym(s) None
  • SMILES O=C(O)[C@H](CCCCNC(OCC1=CC=CC=C1)=O)NC(OCC2C3=C(C4=C2C=CC=C4)C=CC=C3)=O

Description

Fmoc-Lys(Z)-OH is a protected lysine derivative featuring a fluorenylmethoxycarbonyl (Fmoc) group at the α-amino terminus and a benzyloxycarbonyl (Z) group on the side-chain amine. This dual protection enables orthogonal handling in solid-phase peptide synthesis, where the α-amino group remains reactive while the side chain is inert. The Z group ensures stability during coupling steps, minimizing side reactions. This derivative integrates seamlessly into complex peptide sequences requiring selective deprotection.

Synthesis

  • Route1
    • In-stock
      H-Lys(Z)-OH|CS-W007750
      1155-64-2
    • null|null
      28920-43-6
    • ~91%
    • In-stock
      Fmoc-Lys(Z)-OH|CS-W011498
      86060-82-4

    References

    • Huhtiniemi, Tero; Salo, Heikki S.; Suuronen, Tiina; Poso, Antti; Salminen, Antero; Leppaenen, Jukka; Jarho, Elina; Lahtela-Kakkonen, Maija Journal of Medicinal Chemistry, 2011 , vol. 54, # 19 p. 6456 - 6468
  • Route2

    References

    • Schoen, Istvan; Kisfaludy, Lajos Synthesis, 1986 , # 4 p. 303 - 305
  • Route3

    References

    • Kisfaludy, Lajos; Schoen, Istvan Synthesis, 1983 , # 4 p. 325 - 327

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   113.96
  • LogP   5.075
  • H_Acceptors   5
  • H_Donors   3
  • Rotatable_Bonds   11

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