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Structure of 860296-24-8
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6-Chloro-5-fluoropicolinic acid features a highly electron-deficient pyridine core, enabling efficient coupling in late-stage functionalization. The ortho-chloro and meta-fluoro substituents enhance reactivity while maintaining stability under standard conditions. This scaffold integrates readily into bioactive heterocycles and serves as a key building block for pharmaceutical intermediates.
6-Chloro-5-fluoropicolinic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of fluorinated heterocycles and bioactive scaffolds. Its orthogonal halogenation pattern facilitates selective cross-coupling reactions, while the carboxylic acid group supports direct derivatization or amide formation. The compound exhibits excellent bench stability and is compatible with standard purification methods, making it well-suited for scalable synthesis workflows in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: