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CS-W001157 4
Total: USD 88.00

6-Chloropicolinic acid

  • CAS No. 4684-94-0

  • Cat. No. CS-W002451
  • Purity≥98%
  • MDL No.MFCD00155390

*For research and further manufacturing use only, not for direct human use.

6-Chloropicolinic acid|CS-W002451

Structure of 4684-94-0

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General Information

  • CAS No. 4684-94-0
  • Cat. No. CS-W002451
  • Purity ≥98%
  • MDL No. MFCD00155390
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₄ClNO₂
  • Molecular Weight 157.55
  • Synonym(s) 6-Chloro-Picolinic Acid
  • SMILES ClC1=CC=CC(C(O)=O)=N1

Description

6-Chloropicolinic acid is a bench-stable, electron-deficient heterocyclic carboxylic acid featuring a chlorine substituent at the 6-position of the picolinic ring. This configuration enhances its utility in coupling reactions and as a building block for pharmaceutical intermediates and ligands in transition metal catalysis.

Synthesis

  • Route1
    • In-stock
      2-Bromo-6-chloropyridine|CS-W008082
      5140-72-7
    • null|null
      124-38-9
    • ~69%
    • In-stock
      6-Chloropicolinic acid|CS-W002451
      4684-94-0

    References

    • Radl, Stanislav; Hezky, Petr; Proska, Jan; Hejnova, Lucie; Krejci, Ivan Archiv der Pharmazie, 2000 , vol. 333, # 5 p. 107 - 112
  • Route2

    References

    • Kiener, Andreas Angewandte Chemie, 1992 , vol. 104, # 6 p. 748 - 749
  • Route3
    • In-stock
      2-Bromo-6-chloropyridine|CS-W008082
      5140-72-7
    • null|null
      2258-42-6
    • ~75%
    • In-stock
      6-Chloropicolinic acid|CS-W002451
      4684-94-0

    References

    • Gadakh, Amol V.; Chikanna, Dinesh; Rindhe, Sahebrao S.; Karale, Bhausaheb K. Synthetic Communications, 2012 , vol. 42, # 5 p. 658 - 666

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   50.19
  • LogP   1.4332
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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