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Structure of 858515-66-9
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7-Fluoro-1H-indole-3-carboxylic acid features a fluorinated indole core with a carboxylic acid group at the 3-position, offering enhanced electron-withdrawing character and improved metabolic stability. This scaffold integrates readily into bioactive molecules, particularly in medicinal chemistry campaigns targeting CNS disorders and kinase inhibitors. The para-fluorine substitution modulates electronic properties and lipophilicity, enabling fine-tuned interactions within target binding pockets.
7-Fluoro-1H-indole-3-carboxylic acid serves as a valuable building block for the synthesis of substituted indoles and heterocyclic scaffolds. Its fluorinated aryl ring enhances metabolic stability and modulates electronic properties, while the carboxylic acid group enables direct coupling reactions or derivatization. The compound exhibits good bench stability and facilitates efficient functionalization in standard peptide and medicinal chemistry workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: