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Structure of 126921-16-2
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7-Fluoro-1H-indole-3-carbaldehyde features a fluorinated indole core with an aldehyde handle at the 3-position, enabling direct incorporation into bioactive molecule synthesis. The electron-deficient carbonyl group facilitates nucleophilic addition reactions, while the para-fluorine enhances metabolic stability and modulates electronic properties for medicinal chemistry applications.
7-Fluoro-1H-indole-3-carbaldehyde serves as a versatile building block for the synthesis of biologically active indole derivatives. Its electrophilic aldehyde functionality enables facile imine formation, reductive amination, and coupling reactions under standard conditions. The electron-withdrawing fluorine substituent enhances regioselectivity in subsequent functionalizations and improves metabolic stability in downstream pharmaceutical scaffolds. Bench-stable and compatible with common purification methods, it facilitates efficient access to diverse heterocyclic architectures in medicinal chemistry research.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P330-P501
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Lot numbers can be found on the outside label of a product: