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CS-W001157 4
Total: USD 88.00

2-Chloronicotinic acid

  • CAS No. 2942-59-8

  • Cat. No. CS-W017965
  • Purity≥96%
  • MDL No.MFCD00006236

*For research and further manufacturing use only, not for direct human use.

2-Chloronicotinic acid|CS-W017965

Structure of 2942-59-8

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General Information

  • CAS No. 2942-59-8
  • Cat. No. CS-W017965
  • Purity ≥96%
  • MDL No. MFCD00006236
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₄ClNO₂
  • Molecular Weight 157.55
  • Synonym(s) AKOS BBS-00004231
  • SMILES C1=C(C(=NC=C1)Cl)C(O)=O

Description

Kryptofix 22 for synthesis. CAS 23978-55-4, molar mass 262.35 g/mol.

Application

2-Chloronicotinic acid serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling direct incorporation of a halogenated pyridine scaffold. Its ortho-chloro substituent facilitates subsequent cross-coupling reactions, including Suzuki-Miyaura and Buchwald-Hartwig transformations, while maintaining compatibility with common functional groups. The compound exhibits excellent bench stability and ease of purification, making it well-suited for scalable synthesis workflows and downstream derivatization.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352

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Computational Chemistry Data

  • TPSA   50.19
  • LogP   1.4332
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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