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CS-W001157 4
Total: USD 88.00

MeNH-PEG2-OH

  • CAS No. 85475-01-0

  • Cat. No. CS-0209922
  • Purity≥98%
  • MDL No.MFCD12783671

*For research and further manufacturing use only, not for direct human use.

MeNH-PEG2-OH|CS-0209922

Structure of 85475-01-0

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General Information

  • CAS No. 85475-01-0
  • Cat. No. CS-0209922
  • Purity ≥98%
  • MDL No. MFCD12783671
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₃NO₂
  • Molecular Weight 119.16
  • Synonym(s) None
  • SMILES OCCOCCNC

Description

MeNH-PEG2-OH is a bench-stable, moisture-tolerant PEGylated amine with a terminal hydroxyl group. This bifunctional linker features a methylamino anchor and a short ethylene glycol chain, enabling efficient conjugation in bioconjugation workflows. The molecule integrates readily into peptide and polymer architectures under standard conditions.

Application

MeNH-PEG2-OH serves as a versatile bifunctional linker for conjugation and polymer functionalization, combining the amine-reactive N-methylamine group with a terminal hydroxyl for orthogonal derivatization. Its PEG2 spacer provides enhanced solubility and reduced aggregation, enabling efficient synthesis of bioconjugates, peptide-PEG hybrids, and surface-modified nanomaterials. The compound exhibits excellent bench stability and simplifies purification through its polarity profile.

Synthesis

  • Route1
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      67-56-1
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      929-06-6
    • ~%
    • In-stock
      MeNH-PEG2-OH|CS-0209922
      85475-01-0

    References

    • Oku, Tomoharu; Arita, Yoshitaka; Tsuneki, Hideaki; Ikariya, Takao Journal of the American Chemical Society, 2004 , vol. 126, # 23 p. 7368 - 7377
  • Route2
    • null|null
      67-56-1
    • null|null
      929-06-6
    • ~%
    • null|null
      110-91-8
    • In-stock
      2-(2-(Dimethylamino)ethoxy)ethanol|CS-W011078
      1704-62-7
    • In-stock
      MeNH-PEG2-OH|CS-0209922
      85475-01-0

    References

    • Oku, Tomoharu; Ikariya, Takao Angewandte Chemie - International Edition, 2002 , vol. 41, # 18 p. 3476 - 3479
  • Route3
    • In-stock
      2-(2-Chloroethoxy)ethanol|CS-0016058
      628-89-7
    • null|null
      74-89-5
    • ~%
    • In-stock
      MeNH-PEG2-OH|CS-0209922
      85475-01-0
    • null|null
      254448-29-8

    References

    • Lermit; Moggridge Journal of the Chemical Society, 1947 , p. 530,532

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 2735
Class : 8
Packing Group : Ⅱ
Hazard Statements : H227-H302-H314-H335
Precautionary Statements : P210-P260-P261-P264-P270-P271-P280-P301+P330+P331-P304+P340-P330-P363-P370+P378-P403-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   41.49
  • LogP   -0.7853
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   5

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