PEG2-NH-Cbz

Name: PEG2-NH-Cbz
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 145881-74-9
Cat. No. CS-0062254
Purity≥97%
MDL No.MFCD15143230

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

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Structure of 145881-74-9

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General Information

CAS No. 145881-74-9
Cat. No. CS-0062254
Purity ≥97%
MDL No. MFCD15143230
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₂H₁₇NO₄
Molecular Weight 239.27
Synonym(s) None
SMILES O=C(OCC=1C=CC=CC1)NCCOCCO

Description

Benzyl 2-(2-hydroxyethoxy)ethylcarbaMate features a hydroxylated ethylene spacer that enhances solubility and facilitates conjugation in bioconjugation workflows. The carbamate linkage provides stability under physiological conditions while enabling controlled release in targeted applications. This compound serves as a robust linker for peptide and oligonucleotide modifications.

Application

Benzyl 2-(2-hydroxyethoxy)ethylcarbamate serves as a versatile, bench-stable protecting group for primary amines, enabling selective functionalization in complex molecule synthesis. Its hydroxyether side chain enhances solubility and facilitates orthogonal deprotection under mild conditions. The carbamate functionality tolerates a broad range of reaction environments, including nucleophilic substitutions and metal-catalyzed couplings, making it ideal for iterative peptide and heterocycle assembly workflows.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

TPSA 67.79
LogP 0.9217
H_Acceptors 4
H_Donors 2
Rotatable_Bonds 7

Other Classifications

Building Blocks Functional Group Amine

Building Blocks Functional Group Alcohol

Building Blocks Functional Group Ether

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Proteolysis Targeting Chimera Research Reagents

Biochemistry Pharmaceutical Development and Drug Discovery Research Proteolysis Targeting Chimera Research Reagents

Key Words

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PEG2-NH-Cbz

CAS No. 145881-74-9

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