Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

3-(Aminomethyl)pyridin-2(1H)-one hydrochloride

  • CAS No. 85468-38-8

  • Cat. No. CS-0186713
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-(Aminomethyl)pyridin-2(1H)-one hydrochloride|CS-0186713

Structure of 85468-38-8

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 85468-38-8
  • Cat. No. CS-0186713
  • Purity ≥95%
  • MDL No. None
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₉ClN₂O
  • Molecular Weight 160.60
  • Synonym(s) 3-(aminomethyl)pyridine-2(1H)-one hydrochloride
  • SMILES Cl.O=C1NC=CC=C1CN

Description

3-(Aminomethyl)pyridin-2(1H)-one hydrochloride features a pyridinone core with a primary amine tethered via a methylene linker, delivering enhanced solubility and nucleophilicity. The protonated amine facilitates salt formation, improving stability and handling. This scaffold integrates readily into medicinal chemistry campaigns targeting kinase inhibitors and CNS-active compounds.

Application

3-(Aminomethyl)pyridin-2(1H)-one hydrochloride serves as a versatile building block for medicinal chemistry, enabling efficient incorporation of a pyridone-linked aminomethyl group into target molecules. The compound exhibits good bench stability and facilitates straightforward functionalization via amine-directed reactions, including reductive amination and coupling protocols. Its hydrochloride salt form enhances solubility and simplifies purification, making it well-suited for use in high-throughput synthesis and API development workflows.

Synthesis

  • Route1

    References

    • Brana, Miguel F.; Rodriguez, Maria Luz Lopez Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 1297 - 1300

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   58.88
  • LogP   0.2554
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 85468-38-8 sigma85468-38-8 manufacturer85468-38-8 price85468-38-8 structure85468-38-8 SDSbuy 85468-38-885468-38-8 supplier85468-38-8 uses85468-38-8 molecular weightprice of 85468-38-885468-38-8 chemical name formula of 85468-38-8
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label