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CS-W001157 4
Total: USD 88.00

7-Hydroxyheptanoic acid

  • CAS No. 3710-42-7

  • Cat. No. CS-W022546
  • Purity≥97%
  • MDL No.MFCD03095417

*For research and further manufacturing use only, not for direct human use.

7-Hydroxyheptanoic acid|CS-W022546

Structure of 3710-42-7

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General Information

  • CAS No. 3710-42-7
  • Cat. No. CS-W022546
  • Purity ≥97%
  • MDL No. MFCD03095417
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₄O₃
  • Molecular Weight 146.19
  • Synonym(s) None
  • SMILES O=C(O)CCCCCCO

Description

7-Hydroxyheptanoic acid features a terminal carboxylic acid group and a primary hydroxyl moiety separated by a five-carbon aliphatic chain, enabling dual functionalization in synthetic transformations. This linear structure supports integration into esterification, amidation, and polymerization processes under standard conditions.

Application

7-Hydroxyheptanoic acid serves as a versatile building block in synthetic organic chemistry, enabling the construction of bioactive heterocycles and functionalized aliphatic chains. Its bifunctional nature—combining a carboxylic acid and a primary hydroxyl group—facilitates efficient esterification, etherification, and cyclization reactions. The molecule exhibits good bench stability and is compatible with standard protecting group strategies, making it well-suited for iterative synthesis workflows in medicinal chemistry and natural product derivatization.

Synthesis

  • Route1
    • Oxocan-2-one|CS-0723618
      539-87-7
    • ~42%
    • In-stock
      7-Hydroxyheptanoic acid|CS-W022546
      3710-42-7

    References

    • Rajabi, Mehdi; Lanfranchi, Moreno; Campo, Federica; Panza, Luigi Synthetic Communications, 2014 , vol. 44, # 8 p. 1149 - 1154
  • Route2
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      502-42-1
    • ~%
    • In-stock
      7-Hydroxyheptanoic acid|CS-W022546
      3710-42-7

    References

    • Baeyer; Villiger Chemische Berichte, 1900 , vol. 33, p. 860
  • Route3

    References

    • Wada, Carol K.; Frey, Robin R.; Ji, Zhiqin; Curtin, Michael L.; Garland, Robert B.; Holms, James H.; Li, Junling; Pease, Lori J.; Guo, Jun; Glaser, Keith B.; Marcotte, Patrick A.; Richardson, Paul L.; Murphy, Shannon S.; Bouska, Jennifer J.; Tapang, Paul; Magoc, Terrance J.; Albert, Daniel H.; Davidsen, Steven K.; Michaelides, Michael R. Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 19 p. 3331 - 3335

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   57.53
  • LogP   1.0138
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   6

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