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Structure of 85468-38-8
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3-(Aminomethyl)pyridin-2(1H)-one hydrochloride features a pyridinone core with a primary amine tethered via a methylene linker, delivering enhanced solubility and nucleophilicity. The protonated amine facilitates salt formation, improving stability and handling. This scaffold integrates readily into medicinal chemistry campaigns targeting kinase inhibitors and CNS-active compounds.
3-(Aminomethyl)pyridin-2(1H)-one hydrochloride serves as a versatile building block for medicinal chemistry, enabling efficient incorporation of a pyridone-linked aminomethyl group into target molecules. The compound exhibits good bench stability and facilitates straightforward functionalization via amine-directed reactions, including reductive amination and coupling protocols. Its hydrochloride salt form enhances solubility and simplifies purification, making it well-suited for use in high-throughput synthesis and API development workflows.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501
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Lot numbers can be found on the outside label of a product: