Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

6-Hydroxy-2-methylbenzofuran-3-carboxylic acid

  • CAS No. 854515-52-9

  • Cat. No. CS-0456411
  • Purity≥95%
  • MDL No.MFCD12547297

*For research and further manufacturing use only, not for direct human use.

6-Hydroxy-2-methylbenzofuran-3-carboxylic acid|CS-0456411

Structure of 854515-52-9

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 854515-52-9
  • Cat. No. CS-0456411
  • Purity ≥95%
  • MDL No. MFCD12547297
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₈O₄
  • Molecular Weight 192.17
  • Synonym(s) 6-hydroxy-2-methyl-1-benzofuran-3-carboxylic acid
  • SMILES CC1=C(C2=C(C=C(C=C2)O)O1)C(=O)O

Description

6-Hydroxy-2-methylbenzofuran-3-carboxylic acid features a fused benzofuran core with orthogonal hydroxyl and carboxylic acid functionalities, enabling direct conjugation or derivatization. The electron-rich aromatic system enhances reactivity in coupling processes, while the bench-stable hydroxyl group facilitates selective functionalization under mild conditions.

Application

6-Hydroxy-2-methylbenzofuran-3-carboxylic acid serves as a versatile scaffold for the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its orthogonal functional groups—phenolic hydroxyl, carboxylic acid, and methyl substituent—enable selective derivatization via esterification, amidation, or Suzuki coupling. The molecule exhibits good bench stability and facilitates efficient purification by recrystallization or column chromatography, making it well-suited for iterative medicinal chemistry campaigns and process development.

Synthesis

  • Route1

    References

    • ELI LILLY AND COMPANY Patent: WO2007/92751 A2, 2007 ; Location in patent: Page/Page column 27 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   70.67
  • LogP   2.14502
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 854515-52-9 sigma854515-52-9 manufacturer854515-52-9 price854515-52-9 structure854515-52-9 SDSbuy 854515-52-9854515-52-9 supplier854515-52-9 uses854515-52-9 molecular weightprice of 854515-52-9854515-52-9 chemical name formula of 854515-52-9
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label