4-Pyrimidinamine, 6-chloro-5-fluoro-

Name: 4-Pyrimidinamine, 6-chloro-5-fluoro-
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 851984-15-1
Cat. No. CS-0030391
Purity≥98%
MDL No.MFCD14706712

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4-Pyrimidinamine, 6-chloro-5-fluoro-|CS-0030391

Structure of 851984-15-1

Size

Price

Quantity

* Please select Quantity before adding items.

Description

6-Chloro-5-fluoropyrimidin-4-amine features a dual halogenated pyrimidine core, combining chlorine and fluorine substituents at electron-deficient positions. This configuration enhances reactivity in cross-coupling processes while maintaining stability under standard conditions. The primary amine group enables direct incorporation into pharmaceutical scaffolds and functionalized heterocycles.

Application

6-Chloro-5-fluoropyrimidin-4-amine serves as a versatile building block in medicinal chemistry, enabling efficient construction of pyrimidine-based scaffolds. Its orthogonal halogen functionality facilitates palladium-catalyzed cross-coupling reactions, while the primary amine supports derivatization via acylation or alkylation. The compound exhibits good bench stability and is compatible with standard purification protocols, making it well-suited for iterative synthesis campaigns in API development.

General Information

CAS No. 851984-15-1
Cat. No. CS-0030391
Purity ≥98%
MDL No. MFCD14706712
Storage -20°C, sealed storage, away from moisture and light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₄H₃ClFN₃
Molecular Weight 147.54
Synonym(s) 4-Amino-6-chloro-5-fluoropyrimidine
SMILES NC1=NC=NC(Cl)=C1F

Computational Chemistry Data

TPSA 51.8
LogP 0.8513
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Fluoride

Building Blocks Functional Group Chloride

Building Blocks Skeleton Aromatic heterocycle compounds Pyrimidine compounds

Key Words

4-Pyrimidinamine, 6-chloro-5-fluoro- sigma4-Pyrimidinamine, 6-chloro-5-fluoro- manufacturer4-Pyrimidinamine, 6-chloro-5-fluoro- price4-Pyrimidinamine, 6-chloro-5-fluoro- structure4-Pyrimidinamine, 6-chloro-5-fluoro- SDSbuy 4-Pyrimidinamine, 6-chloro-5-fluoro-4-Pyrimidinamine, 6-chloro-5-fluoro- supplier4-Pyrimidinamine, 6-chloro-5-fluoro- uses4-Pyrimidinamine, 6-chloro-5-fluoro- molecular weightprice of 4-Pyrimidinamine, 6-chloro-5-fluoro-4-Pyrimidinamine, 6-chloro-5-fluoro- chemical name formula of 4-Pyrimidinamine, 6-chloro-5-fluoro-

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

4-Pyrimidinamine, 6-chloro-5-fluoro-

CAS No. 851984-15-1

Recommended Products